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Cognitive training, intervention in early dementia, the effect is obv

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Recently, Jia Jianping, chief expert of neurology, Xuanwu Hospital, Beijing Medical University of China, published the latest research results in Alzheimer's Disease and Dementia, a leading international journal in the field of dementia. They confirmed that cognitive training can improve the overall cognitive function of patients with mild vascular cognitive impairment through randomized controlled trials, and revealed that neuroplasticity is the intrinsic mechanism of cognitive improvement. The results of this study provide a powerful means for the prevention and early intervention of dementia in clinic.


Vascular cognitive impairment is the second leading cause of cognitive impairment, second only to Alzheimer's disease. A national multi-center study led by Jia Jianping shows that there are more than 20 million patients with mild cognitive impairment in China, among which vascular mild cognitive impairment ranks first, accounting for 42%. However, there are still no approved effective therapeutic drugs.


As a non-drug treatment method, the role of cognitive training in the prevention and early intervention of dementia has attracted more and more attention in recent years, and it has become an international academic hotspot. In 2016, Jia Jianping led the research. In this study, 60 patients were randomly divided into cognitive training intervention group and active control group. The intervention group received cognitive training for 5 days a week and 30 minutes a day for 7 weeks, while the control group received simple computer operation tasks with the same time and fixed difficulty. The results showed that the Montreal Cognitive Assessment Scale score of the intervention group increased from 21.87 to 25.22, while that of the control group decreased from 21.23 to 21.15. Further resting-state functional magnetic resonance analysis showed that the connection between default network and executive control network was significantly enhanced in the intervention group, suggesting that neuroplasticity is the intrinsic mechanism of cognitive training to improve cognitive function of patients.


It is reported that this is the first international study on cognitive training intervention for mild vascular cognitive impairment. The cognitive training system adopted by the Research Institute was developed by the research team.


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